Jan. 12, 2021

 DIABETES-Useful information about different causes and solution.



There are many different types of sugars. As we know the most common one is the white table sugar, which is half glucose half fructose. Lactose is a milk sugar and maltose can be found in beer. However, the worst of the worst is pure fructose, and the reason is that fructose not only causes insulin resistance, fructose also causes Leptin resistance (Leptin is a hormone made in fat cells). If you are Leptin resistant your brain no longer knows whether you are full or not and you tend to overeat. Therefore, you need to be sure that you eliminate from your diet fructose from fruits and HFCS (high fructose corn syrup). HFCS is used to sweeten most processed food and soft drinks. Another reason to avoid fructose is that fructose controls the conversion of your Purines into Uric Acid which gives you the Gout.

Fructose is bad but it doesn’t mean you can’t eat fruit. Fruit contains vitamin C and fibre which slow down the release of sugar to your blood stream and have lesser effect on receptors. You can eat any whole fruit but you can’t have honey, agave, or drink fruit juices. 

You also need to remember that all refined carbohydrates, when eaten, are converted very quickly to sugar spiking your blood sugar levels. 



 Trans fats (any liquid vegetable oils converted to solid fats) gum up insulin receptors and contribute to insulin resistance. There are many health implications from consuming trans fats, e.g. an increase in LDH - a bad cholesterol, therefore, it is better to avoid those fats as much as possible. Unfortunately, they are commonly used in many processed foods.

Another reason for not consuming vegetable fats such as soy, sunflower, safflower and canola oils, is that insulin upregulates enzymes that control conversion of those fats into Arachidonic Acid. Arachidonic acid is a precursor to pro-inflammatory hormone which gives pain, inflammation, and degenerative diseases. 

The sensitivity of all the receptors of our body are based upon a balance of our Omega 3 to Omega 6 ratio. The ratio should be 6:3. As the most foods we are eating contain mainly Omega 6 oils, it is advisable to increase consumption of foods containing Omega 3 or take a supplement.

Accumulation of one type of fat called Ceramides outside fat cells, dysregulate lipid (fat) metabolism and can lead to lipotoxicity. Concentration of those toxic fats in the blood plasma and the tissue are associated with risk of developing type 2 diabetes.  Research on Alzheimer’s disease also showed that Ceramides-toxic fats, create insulin resistance in the brain.




  1. Reduce consumption of carbohydrates such as flour, rice and potatoes. Make sure you eat them in combination with good proteins such as fish and lean meat. This way you slow down the release of sugars into the blood stream.
  2. Read food labels to avoid Trans Fats. Use coconut oil in cooking. Alternative sources for increasing energy production in your cells without going into ketoacidosis is medium chain saturated triglycerides – coconut oil. Diabetic ketoacidosis is a serious complication of diabetes that occurs when your body produces high levels of blood acids called ketones. The condition develops when your body can’t produce enough insulin.
  3. Avoid foods high in Ceramides such as soybeans, dairy, eggs, sweet potatoes, wheat and rice.
  4. Increase consumption of foods high in Omega 3 such as fish and other seafood (especially cold-water fatty fish, such as salmon, mackerel, tuna, herring, and sardines). Nuts and seeds are also an excellent source of Omega 3 fats. However, if you don’t like fish, you should take a supplement of Omega 3. A dose of 200 to 300 mg should be enough per day, taking with food.
  5. Use Cinnamon as often as possible adding to your tea or coffee. There is a lot of evidence that cinnamon sharpens the sensitivity to the insulin receptors.
  6. Take a supplement of Chromium Picolinate. Lots of studies show chromium sharpens the sensitivity of the insulin receptors. A dose of no more than 1000 micg per day with food. 
  7. Exercise is an excellent way to help people tprotect themselves against insulin resistance. 



Feb. 19, 2018

Nutritionist vs Dietitian vs Nutritional Therapist.

I get asked this all the time. Here's my take on it.

A nutritionist is anybody who claims to be an expert in the field of nutrition. This is a broad description because some nutritionists have not studied, meaning they are not appropriately qualified and do not belong to a governing body. When taking advice from a nutritionist always check they have studied, are registered and belong to a governing body. 

A dietitian is somebody who has a degree in Nutrition and Dietetics. Dietitians generally work with the NHS, although some will work directly with the public. I am not a dietitian.

A nutritional therapist is somebody who is appropriately qualified and has a recognized qualification in Nutritional Therapy. Nutritional therapists usually work in private practice offering bespoke health plans, using nutrition and lifestyle interventions to help support the body towards maintaining health. I am a qualified and registered nutritional therapist. I also refer to myself as a nutritionist because many people are not aware of what a nutritional therapist is. When taking advice from a nutritional therapist always check they have appropriately qualification, amd they are registered and belong to a regulated governing body.

As a nutritional therapist I specialized in weight management, hormonal health, stress and digestion.



Oct. 14, 2017

A study published in the the Canadian Medical Association Journal revealed that people low in vitamin B12 had an increase risk of a fatal heart attack and stroke.

The study focused on the relationship between homocysteine, B-12 and carotid artery plaque.

The study showed that higher blood levels of B vitamins are related to lower concentrations of homocysteine leading to decrease plaquing in the carotid arteries. However, an elevated blood homocysteine level revealed a strong risk factor for heart disease and stroke.

How the Study was Conducted
The study examined 421 people with the average age being 66. Vitamin B12, homocysteine levels and degree of plaque in the carotid arteries (via ultrasound) were evaluated.

The Results

Seventy-three patients (17%) had vitamin B12 deficiency with significant elevation of homocysteine. In addition and most important, carotid plaque was significantly larger among the group of patients who had deficiency of vitamin B12 In conclusion, the authors found that low blood vitamin B12 levels are a major cause of elevated homocysteine levels and increased carotid plaque area.

Dr. Grisanti's Comments
Have your physician order a blood homocysteine test and a methylmalonic acid (MMA) test. This is the most specific test for B12 status NOT the serum B-12 blood test.

Jul. 31, 2017

The brain is the most nutrient-dependent, energy-dependent and toxin- and stress-vulnerable organ in the body. The gut and the brain are very tightly linked. In the gut-brain axis, damage to one is often damage to the other.



Concussion is a good example. When a blow to the head or severe jolt causes a concussion, the damage to the neurons has a parallel in damage to the gut lining. The tight junctions of the lining almost immediately open up and become permeable. This produces inflammatory cytokines that can penetrate the blood-brain barrier, leading to additional brain inflammation. In other words, when the gut is on fire, so is the brain.

If the sudden intestinal permeability caused by a concussion goes untreated, the concussion symptoms will be worse, due to the additional inflammation. The gut permeability may not resolve by itself, which could contribute to making the concussion symptoms linger on for weeks instead of days. Intestinal permeability may also play a role in those patients who go on to develop post-concussion syndrome by causing ongoing brain inflammation.

So, in addition to treating the concussion itself with nutrition, the intestinal permeability, particularly the release of occludin and zonulin, needs to be immediately addressed.

The intercellular permeability of the gut lining can be treated through repair and regeneration with xanthohumol. A natural phenol derivative of hops, xanthohumol has a very extensive (more than 250 publications in preclinical science) record of efficacy and safety. In the brain, xanthohumol acts as an antioxidant and anti-inflammatory; it also helps with the biogenesis of mitochondria in damaged neurons. In the gut, the polyphenols are strongly anti-inflammatory. They modify the inflammatory kinases in favor of antioxidant pathways and, just as important, block the kinases in the cell-damaging inflammatory pathways for tumor necrosis factor, COX-2, and others.

On a chronic level, we know that neurodegenerative diseases such as Alzheimer's, depression, and anxiety may not be exclusively triggered within the brain. When the intestinal barrier is breached, so is the blood-brain barrier. Inflammation from circulating gut-derived lipopolysaccharides (LPS) pass through the blood-brain barrier and have been linked to a number of neurodegenerative disorders. In particular, LPS stimulates the production of IgA, IgG, and IgM antibodies that can cross-react with tissues and induce autoimmune disease and neurodegeneration. 

Treating brain inflammation caused by gut inflammation starts with removing the cause through a modified elimination food plan and the removal of pathogens. Anti-inflammatory supplements, such as berberine, and digestive enzymes, such as lipase and amylase, help restore the gut lining. The next step is to reinoculate and regenerate the gut with a powdered nutritional supplement if needed, continuation of the modified elimination diet, and the addition of probiotics, vitamin D, alpha-lipoic acid, and specialized pro-resolving mediators (SPMs). Xanthohumol is also very helpful for regenerating intestinal mucosa.

Once the process is underway, retesting is important to see the gains and make any necessary adjustments to the treatment plan. As healing progresses, retaining the gains with a better diet and appropriate supplements becomes the focus of treatment.

Healing the intestinal barrier is only half the equation. The brain inflammation needs to be treated as well. Low-level laser therapy (LLLT) is a valuable tool for improving neurological function. In concussion patients, it has been shown to help reduce inflammation, modulate oxidative stress and nitric oxide production, and down-regulate pro-inflammatory microglial cytokine expression.

LLLT is also valuable for reducing inflammation of the vagus nerve. The longest of the cranial nerves, the vagus is often called the great wanderer for the way is wanders through the visceral organs. A major function of the vagus nerve is preventing inflammation. In the gut, the vagus nerve endings sense the chemical signals of inflammation, such as cytokines and tumor necrosis factor, and send messages to the brain telling it to release anti-inflammatory neurotransmitters via the cholinergic anti-inflammatory pathway. When the brain-gut axis is disrupted, the vagus nerve is affected and the messages back and forth are garbled or don't get through at all. Decreased vagal nerve activity has some serious effects on the gut. Hydrochloric acid and pancreatic enzyme secretion is reduced, as is bile secretion. The parietal cells in the stomach, which are responsible for producing intrinsic factor, don't work as well, leading to reduced absorption of B vitamins. 

We know that post-injury vagal nerve stimulation (VNS) after a concussion can help prevent the breakdown of epithelial cells in the gut and keep the tight junctions from opening. This only works when administered within 90 minutes of the injury, however. Later on, stimulation of the vagus nerve with LLLT using 405 nm violet lightcan help to restore communications and reduce inflammation.

Treatment modalities such as those discussed here help repair the integrity of the gut lining and the blood-brain barrier. They're a hopeful new approach to restoring the functionality of the gut-brain axis and returning the body to harmony.  

Jul. 7, 2017

Autoimmune diseases are the most often occurring forms of chronic illness. More people suffer from these conditions than from cancer or heart disease, yet most people don’t even know what these conditions are. Many people with autoimmune diseases suffer with their symptoms because they can’t figure out what’s wrong or can’t get to the root of the problem!

The answer is NUTRITIONAL THERAPY where I focus on the causes and reversing these chronic diseases.